TABLE 3

Cleveland Clinic MICU COVID-19 workup checklist (updated 4/15/2020)

1. Upon admission:
• Complete blood count with differential, basic metabolic panel (BMP), liver function tests (LFTs), lactate dehydrogenase (LDH), C-reactive protein (CRP), fibrinogen, D-dimer, high-sensitivity troponin, NT-proBNP, creatine kinase (CK), CK-MB, procalcitonin, ferritin, aPTT, INR, IL-6, electrocardiography
2. Follow-up:
• Troponin: If troponin upon admission is elevated, then check troponin daily for 3 days or clinical deterioration
• CRP: Check CRP daily, if it is elevated, consider checking triglyceride (TG), ferritin, fibrinogen, LFTs
• TG: Check TG every 48 hrs while on propofol
• D-Dimer, ferritin, PT/INR, aPTT: Monitor every 48 hrs for 3 times
 • If patient has evidence of diffuse vascular coagulation (DIC), then check fibrinogen, PT/INR and aPTT
 • Stop monitoring ferritin if patient is on Tocilizumab
 • Stop monitoring D-dimer and PT/aPTT if patient is on therapeutic anticoagulation
3. Chest x-ray (CXR):
• Perform CXR upon admission after all lines and tubes, then further CXR should perform only if it will change clinical management
4. Electrocardiography:
• Perform upon admission, and check QTc interval from bedside monitor