Immunotherapeutic strategies for COVID-19
Kinase inhibitors |
Tofacitinib, baricitinib, ruxolitinib, others |
Targeted therapy |
Inhibitors of interleukin 1 (IL-1), IL-6, tumor necrosis factor, and granulocyte macrophage colony-stimulating factor; interferon gamma |
Tolerogenic therapies |
T-cell regulators, low-dose IL-2 |
Cellular therapies |
Natural killer cell therapies, antiplasmacytoid dendritic cell, others |
Passive therapy |
Intravenous immune globulin, immune plasma, specific antibodies |
Nonspecific therapies |
Glucocorticoids, calcineurin inhibitors, mammalian target of rapamycin inhibitors |