TABLE 1

Anticoagulation after percutaneous coronary intervention in patients with atrial fibrillation

Time after PCILow risk of stroke, low risk of bleedingaHigh risk of stroke, low risk of bleedingLow risk of stroke, high risk of bleeding
0–1 monthDOAC plus P2Y12 inhibitorDOAC plus P2Y12 inhibitor plus aspirinDOAC plus P2Y12 inhibitor
1–6 monthsDOAC plus P2Y12 inhibitorDOAC plus P2Y12 inhibitorDOAC plus P2Y12 inhibitor
6–12 monthsDOAC plus P2Y12 inhibitorDOAC plus P2Y12 inhibitorDOAC only
After 12 monthsDOAC only, discuss risks and benefitsDOAC only, discuss risks and benefitsDOAC only, discuss risks and benefits
  • a For example, with CHA2DS2-VASc score of 0 or 1 and HAS-BLED score of 0–2.

  • DOAC = direct-acting oral anticoagulant; PCI = percutaneous coronary intervention