Effects of hypercortisolism
| Organ system | Manifestation |
|---|---|
| Cardiovascular | Hypertension, thromboembolism, cardiomyopathy |
| Metabolic | Glucose intolerance/diabetes, hyperlipidemia, obesity |
| Reproductive | Menstrual irregularities, hirsutism, changes in libido, virilization |
| Dermatologic | Easy bruisability, striae, skin atrophy, hyperpigmentation, oily skin |
| Musculoskeletal | Proximal muscle wasting, osteopenia/ osteoporosis |
| Neuropsychiatric | Psychosis, emotional lability, depression, anxiety, sleep apnea |
| Immunologic function | Increased susceptibility to fungal and bacterial infection, opportunistic infections |
| Ophthalmologic | Glaucoma, cataracts, central serous chorioretinopathy, hypertensive retinopathy |