TABLE 2

Thromboprophylaxis for patients with COVID-19 or patients under investigation

If D-dimer is < 3,000 FEU or unknown, and:

  • No renal impairment: enoxaparin 40 mg every 24 hours

  • Creatinine clearance 10–30 mL/hour: enoxaparin 30 mg every 24 hours

  • Creatinine clearance < 10 mL/hour, acute kidney injury, or dialysis: heparin 5,000 units every 12 hours

If D-dimer is ≥ 3,000 FEU or critically ill patient (independent of D-dimer level), and:

  • No renal impairment: enoxaparin 40 mg every 12 hours

  • Creatinine clearance 10–30 mL/hour: enoxaparin 40 mg every 24 hours

  • Creatinine clearance < 10 mL/hour, acute kidney injury, or dialysis: heparin 7,500 units every 12 hours