TABLE 1

Absolute change in hemoglobin A1c with SGLT-2 inhibitor monotherapy compared with placebo

EmpagliflozinaCanagliflozinbDapagliflozincErtugloflozind
Low doseHigh doseLow doseHigh doseLow doseHigh doseLow doseHigh dose
−0.74%−0.85%−0.90%−1.20%−0.54%−0.60%−0.50%−0.50%

  • ↵a Empagliflozin low dose = 10 mg, high dose = 25 mg.6

  • ↵b Canagliflozin low dose = 100 mg, high dose = 300 mg.5

  • ↵c Dapagliflozin low dose = 5 mg, high dose = 10 mg.7

  • ↵d Ertugloflozin low dose = 5 mg, high dose = 15 mg.8