TABLE 5

Reported cases of COVID-19-associated immune thrombocytopenic purpura

Case	Presenting symptoms	COVID symptoms present before or on admission?	Hospital day of decrease in platelet count	Initial platelet count (× 10⁹/L)	First ITP intervention	Platelet count after first ITP intervention (× 10⁹/L)	Second ITP intervention (if applicable)	Platelet count after second ITP intervention (×10⁹/L)
Hindilerdin et al²²	Easy bruising, fatigue, fever, dry cough	Yes	Day 0	10	IVIG 1 g/kg × 2 days	25	Prednisolone 1 mg/kg/day × 10 days	100
Tsao et al²³	Rash, purple lesions in mouth, bruising	Yes	Day 0	5	IVIG 1 g/kg once	320	N/A	N/A
Artru et al²⁴	Dyspnea, fever, cough, asthenia	Yes	Day 4	1	IVIG 0.4 g/kg × 5 days Dexamethasone 40 mg/day × 4 days	30	Dexamethasone 40 mg/day × 4 days	75
Bennett et al²⁵	Fever, dyspnea, diarrhea, cough	Yes	Day 0	< 3	IVIG 1g/kg × 2 days	105	N/A	N/A
Levesque et al²⁶	Dyspnea, dry cough, fever	Yes	Day 20	23	IVIG 1 g/kg × 2 days Dexamethasone 40 mg × 4 days	< 10	Romiplostim daily × 10 days Vincristine × 1 day Methylprednisolone 500 mg IV × 4 days	178
Murt et al²⁷	Petechiae, easy bruising	Yes	Day 0	9	IVIG 2 g/kg × 2 days	54	N/A	N/A
Bomhof et al²⁸
Patient 1	Oral mucosal petechiae, spontaneous skin hematomas	Yes	Day 0	< 3	Platelet transfusion IVIG 1 g/kg × 2 days	47	Dexamethasone	51
Patient 2	Petechiae, bleeding from hemorrhoids, epistaxis	Yes	Day 0	2	Platelet transfusion Dexamethasone 40 mg daily × 4 days	2	IVIG	32
Patient 3	Fever, coughing, dyspnea	Yes	Day 12	3	N/A	N/A	N/A	N/A
Granat et al (current case)	None	N/A	0	3	Platelet transfusion Dexamethasone 40 mg × 1 day	67	Prednisone 1 mg/kg × 4 days	268

ITP = immune thrombocytopenic purpura; IVIG = intravenous immunoglobulin; N/A = not available