Protocol for the peanut-derived oral immunotherapy agent
| Phase | Duration | Dosage |
|---|---|---|
| Dose-escalation | Single day | 5 levels: 0.5, 1, 1.5, 3, and 6 mg; increasing doses every 20–30 minutes |
| Up-dosing | Months | 11 levels: 3, 6, 12, 20, 40, 80, 120, 160, 200, 240, and 300 mg daily; increasing doses at visits every 2 weeks |
| Maintenance | Months to years | 300 mg daily |
Adapted from information in reference 15.