Indications for initiating treatment of suspected VITT
| Thrombocytopenia and a positive PF4-polyanion test in the presence of thrombosis |
| High clinical suspicion of VITT based on the presence of thrombosis and thrombocytopenia after vaccination, even when PF4-polyanion ELISA results are pending |
| Thrombocytopenia and a positive PF4-polyanion ELISA, with or without a very high or increasing D-dimer level, even in the absence of thrombosis |
ELISA = enzyme-linked immunosorbent assay; VITT = vaccine-induced thrombotic thrombocytopenia