TABLE 1

Distinct features of influenza and COVID-19

InfluenzaCOVID-19
SeasonalityFall-winterYear-round
Annual incidence
 Overall8% (3% –11%)6%–8%
 Children20% (unvaccinated)Not applicable (no vaccine)
 Adults10% (unvaccinated)6%–8% (unvaccinated)
Age distributionChildren > adultsAdults > children
Incubation period (days)1 –4 days2– 14 days
Duration of infectivity1 day before to 7 days after onset of illness2 days before to 10 (20 for severe cases) days after onset of illness
Onset of symptomsMore acuteMore subacute
Super-spreaders (1 person infects 8 persons)Not reported1%
Typical or characteristic features at onset of illnessFever, headache, dry coughLoss of sense of taste or smell
Severity of illness
 Asymptomatic5%–50%30%–40%
 Symptomatic
  Mild98%80%
  Moderate1%–2%15%
  Severe0.2%5%
 Fatal0.04%–0.1%3%–4%
Duration of acute illness5–7 days2– 6 weeks
Incidence of long-term symptoms lasting longer than 4 weeksClinically silent viral shedding for weeks to months in immunocompromised individuals60%–70% regardless of viral shedding
ComplicationsPneumoniaDeep venous thrombosis and pulmonary embolism
Exacerbation of underlying chronic heart and lung diseasesMultisystem inflammatory disorders
  • Data from references 11 and 12.