TABLE 2

Screening instruments for post-intensive care unit emotional impairment

Screening toolNumber of questionsInterpretation of resultsFurther information
Depression
 Hospital Anxiety and Depression Scale (HADS)14 total, 7 focusing on depression symptoms0-7 Normal
8-10 Borderline abnormal (borderline case)
11-21 Abnormal
Validated in ICU population
 Hamilton Depression Rating Scale (HAM-D)21 items, scoring based on first 17 items10-13 Mild
14-17 Mild to moderate
> 17 Moderate to severe
 Beck Depression Inventory-II21 items (13-item short-form available)0-14 Minimal
14-19 Mild
20-28 Moderate
> 29 Severe
 Patient Health Questionnaire-9 (PHQ-9)91-4 Minimal
5-9 Mild
10-14 Moderate
15-19 Moderately severe
20-27 Severe
Anxiety
 Hospital Anxiety and Depression Scale (HADS)14 total, 7 focusing on depression symptoms0-7 Normal
8-10 Borderline abnormal
11-21 Abnormal
Validated in ICU population
 Hamilton Anxiety Rating Scale (HAM-A)140-13 Minimal
14-17 Mild
18-24 Moderate
25-30 Severe
 Generalized Anxiety Disorder 7-item (GAD-7)70-4 Minimal
5-9 Mild
10-14 Moderate
15-21 Severe
PTSD
 Impact Event Scale-Revised (IES-R)2224-32 Clinical concern for PTSD
33-38 Clinical cutoff for probable PTSD diagnosis
> 39 Significant enough symptoms to suppress immune system (even 10 years after impact event)
Validated in ICU population
 Impact Event Scale-6 (IES-6) (abbreviated IES-R)6Calculated as mean of 6 questions with higher scores representing more-severe PTSD symptomsValidated in ARDS survivors47
 Posttraumatic Symptom Scale, 10 items (PTSS-10)10Cutoff score > 35 predicts PTSD (PTSS-High)Validated in ICU population
Good reliability
Detects PTSD symptoms but does not diagnose PTSD
 PTSD Checklist for DSM-5 (PCL-5)20Total score of 31-33 or higher suggests patient may benefit from PTSD treatment
 Abbreviated Posttraumatic Checklist (PCL-C)6> 14 suggestive of difficulties with posttraumatic stress
  • ARDS = acute respiratory distress syndrome; DSM = Diagnostic and Statistical Manual of Mental Disorders; ICU = intensive care unit; PTSD = posttraumatic stress disorder

  • Based on information in references 5, 40, and 4547.