Clinical syndromes after discontinuing antidepressants
| Condition | Category | Onset, duration | Symptoms |
|---|---|---|---|
| Discontinuation syndrome | Acute withdrawal | Onset 36–96 hours Duration < 6 weeks | New symptoms not present before antidepressant was started or stopped |
| Rebound | Onset 36–96 hours Duration < 6 weeks | Greater severity of original symptoms | |
| Persistent withdrawal syndrome | Onset 24 hours to 6 weeks Duration > 6 weeks | New symptoms and/or greater severity of original symptoms | |
| New episode | Relapse | Onset < 6 weeks Duration variable | Original symptoms at original severity |
| Recurrence | Onset > 6 months Duration variable | Original symptoms at original severity | |
Based on information in reference 9.