Diagnostic criteria for anaphylaxis
| Anaphylaxis is highly likely when any 1 of the following 3 criteria is met: | |
|---|---|
| 1 | Sudden onset of symptoms (minutes to several hours) with involvement of skin and/or mucosa (eg, generalized hives, itching or flushing, swollen lips/tongue/uvula), AND at least one of the following: Respiratory symptoms or signs (eg, shortness of breath, wheezing, cough, hypoxemia) Hypotension or other symptoms of target-organ dysfunction (eg, collapse, incontinence) |
| 2 | Sudden onset of 2 or more of the following after exposure to a likely allergen or other trigger for that patient (minutes to several hours): Skin or mucosal membrane symptoms Respiratory symptoms Hypotension or other symptoms of target-organ dysfunction Gastrointestinal symptoms such as abdominal pain or vomiting |
| 3 | Hypotension occurring acutely (minutes to several hours) after exposure to a known or established allergen for that patient. Hypotension is defined as the following: Adults: Systolic blood pressure < 90 mm Hg, or a decrease > 30% from patient’s baseline Infants and children: Low systolic blood pressure (age-specific) or a decrease > 30% in systolic pressure |
Based on information from reference 1.