Statins and diabetes: Results of 13 trials

Trial and statinRisk of diabetes with statin use
Trial of atorvastatin
ASCOT-LLA (Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm)Higher
Trials of simvastatin
HPS (Heart Protection Study)Higher
4S (Scandinavian Simvastatin Survival Study)Higher
Trials of rosuvastatin
JUPITER (Justification for the Use of Statins in Primary Prevention: an Intervention Trial Evaluating Rosuvastatin)Higher
CORONA (Controlled Rosuvastatin Multinational Trial in Heart Failure)Higher
GISSI HF (Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto Miocardico–Heart Failure)Higher
Trials of pravastatin
WOSCOPS (West of Scotland Coronary Prevention StudyLower
LIPID (Long-Term Intervention with Pravastatin in Ischaemic Disease)Lower
MEGA (Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese)Higher
ALLHAT-LLT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial)Higher
GISSI PREVENZIONE (Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto Miocardico–Prevenzione)Lower
PROSPER (Prospective Study of Pravastatin in the Elderly at Risk)Higher
Trial of lovastatin
AFCAPS/TexCAPS (Air Force/Texas Coronary Atherosclerosis Prevention Study)Lower
  • Based on information from reference 5.