Statins and diabetes: Results of 13 trials
| Trial and statin | Risk of diabetes with statin use |
|---|---|
| Trial of atorvastatin | |
| ASCOT-LLA (Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm) | Higher |
| Trials of simvastatin | |
| HPS (Heart Protection Study) | Higher |
| 4S (Scandinavian Simvastatin Survival Study) | Higher |
| Trials of rosuvastatin | |
| JUPITER (Justification for the Use of Statins in Primary Prevention: an Intervention Trial Evaluating Rosuvastatin) | Higher |
| CORONA (Controlled Rosuvastatin Multinational Trial in Heart Failure) | Higher |
| GISSI HF (Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto Miocardico–Heart Failure) | Higher |
| Trials of pravastatin | |
| WOSCOPS (West of Scotland Coronary Prevention Study | Lower |
| LIPID (Long-Term Intervention with Pravastatin in Ischaemic Disease) | Lower |
| MEGA (Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese) | Higher |
| ALLHAT-LLT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial) | Higher |
| GISSI PREVENZIONE (Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto Miocardico–Prevenzione) | Lower |
| PROSPER (Prospective Study of Pravastatin in the Elderly at Risk) | Higher |
| Trial of lovastatin | |
| AFCAPS/TexCAPS (Air Force/Texas Coronary Atherosclerosis Prevention Study) | Lower |
Based on information from reference 5.