Sporadic and syndromic fundic gland polyps compared

FeatureSporadic fundic gland polypsSyndromic (FAP-associated) fundic gland polyps
Number< 20≥ 20, often hundreds8
LocationBody of the stomachMostly in the body of the stomach, but can also be seen in the antrum
Presence of dysplasiaRareIn 25%–40%5
AgeOlder; average age 40Under age 40
SexMore common in females than malesIncidence similar in both sexes6
Other EGD findingsNone knownConcurrent duodenal adenomas can be seen7
  • EGD = esophagogastroduodenoscopy; FAP = familial adenomatous polyposis

  • Based on information in references 58.