TABLE 1

Diagnostic criteria for postural orthostatic tachycardia syndrome

All of the following criteria are necessary:
A sustained increase in heart rate by ≥ 30 beats per minute within 10 minutes of standing or head-up tilt in adults (or ≥ 40 beats per minute for patients ages 12–19) without orthostatic hypotension (a fall in systolic blood pressure ≥ 20 mm Hg or diastolic blood pressure ≥ 10 mm Hg)
Associated symptoms of orthostatic intolerance that are worse with standing (light-headedness, fatigue, palpitations, tremulousness, blurred vision, syncope) and improve with recumbency
Symptom duration of at least 3 months
Absence of other conditions to explain sinus tachycardia (prolonged bed rest, medications, hyperthyroidism, anorexia nervosa, anemia, pain, fever, infection, dehydration)
  • Based on information in reference 1, 2, 4, and 5