Screening for common adverse effects of corticosteroids in patients with chronic graft-vs-host disease
| Adverse effects | Screening | |
|---|---|---|
| Metabolic and endocrine | Hyperglycemia Adrenal insufficiency Weight gain | Measure hemoglobin A1c every 3 months Monitor complete metabolic panel and blood pressure Weigh at every visit |
| Orthopedic | Osteoporosis Avascular necrosis Myopathy | Obtain dual-energy x-ray absorptiometry scan within first year after hematopoietic cell transplant Obtain radiograph if symptoms are present Ask about muscle pain and weakness |
| Neuropsychiatric | Insomnia, mania, psychosis | Ask about sleep and psychiatric symptoms |
| Cardiovascular | Hypertension Fluid retention | Check blood pressure at every visit Weigh at every visit |
| Gastrointestinal | Gastritis, peptic ulcer disease | Ask about gastrointestinal symptoms |
| Hematologic | Leukocytosis | Monitor complete blood cell count |
| Dermatologic | Acne, hirsutism | Perform skin examination at every visit |
Based on information from reference 10.