TABLE 1

Buprenorphine formulations and indications

Generic name and administration route	Brand name	Dose formulations	US Food and Drug Administration indication
Buprenorphine hydrochloride for intravenous or intramuscular administration	Buprenex injection	0.3 mg/mL	Acute moderate-to-severe pain
Buprenorphine transdermal system	Butrans	5 μg/hour 7.5 μg/hour 10 μg/hour 15 μg/hour 20 μg/hour	Chronic pain
Buprenorphine buccal film	Belbuca	75 μg 150 μg 300 μg 450 μg 600 μg 750 μg 900 μg	Chronic pain
Buprenorphine extended-release injection for subcutaneous use	Sublocade	300 mg/1.5 mL monthly after induction for first 2 months 100 mg/0.5 mL maintenance dose monthly (can increase to 300 mg)	Opioid use disorder
Buprenorphine sublingual tablets	Subutex	2 mg 8 mg	Opioid use disorder
Buprenorphine/naloxone sublingual film	Suboxone	2 mg/0.5 mg 4 mg/1 mg 8 mg/2 mg 12 mg/3 mg	Opioid use disorder
Buprenorphine/naloxone sublingual tablets	Suboxone	2 mg/0.5 mg 8 mg/2 mg	Opioid use disorder
Buprenorphine/naloxone sublingual rapid-dissolve tablets	Zubsolv	0.7 mg/0.18 mg 1.4 mg/0.36 mg 2.9 mg/0.71 mg 5.7 mg/1.4 mg 8.6 mg/2.1 mg 11.4 mg/2.9 mg	Opioid use disorder