TABLE 3

Surgical treatments for obstructive sleep apnea

TreatmentIndicationsReduction in apnea-hypopnea indexCaveatsPossible predictors of success
Hypoglossal nerve stimulation100102Moderate to severe obstructive sleep apnea not tolerating CPAP; BMI < 40 kg/m2; AHI 15–10068%Tongue weakness, infection, hematoma, pneumothoraxAnteroposterior collapse, female, lower BMI and AHI, higher arousal threshold
Uvulopalatopharyngoplasty99Excessive daytime sleepiness, AHI > 1533%; with laser-assisted uvuloplasty, 18%Velopharyngeal insufficiency, nasal regurgitation, foreign body sensationVelopharyngeal/retropharyngeal airway collapse
Tongue reduction99Macroglossia34% (radiofrequency ablation)Bleeding, tongue edema causing airway obstruction, wound infectionLarge base of tongue, macroglossia
Maxillomandibular advancement99Failure of other options, especially CPAP; can be a primary option with jaw deformities87%Change in appearance, dental or facial numbnessCraniofacial deformities with retruded mandible
  • AHI = apnea-hypopnea index; BMI = body mass index; CPAP = continuous positive airway pressure therapy