TABLE 3

Variations in society recommendations for the management of gastric intestinal metaplasia

Geographic locationSociety recommendations
East AsiaEndoscopic or radiographic screening of all men and women at age 50 or older29
In patients with gastric intestinal metaplasia and high-risk features, endoscopy recommended in 1 to 3 years
EuropePatients with extensive gastric intestinal metaplasia should undergo endoscopic surveillance every 3 years
Consider endoscopic surveillance in patients with gastric intestinal metaplasia limited to the corpus or antrum of the stomach but with a family history of gastric cancer, persistent Helicobacter pylori infection, incomplete gastric intestinal metaplasia, or autoimmune gastritis30
United StatesAGA recommends against routine endoscopic surveillance after gastric intestinal metaplasia is detected in the general population, but if H pylori is detected, treatment is encouraged
Patients with gastric intestinal metaplasia and risk factors associated with progression could be considered for endoscopic surveillance every 3 to 5 years if the patient favors surveillance (which has an unclear impact on mortality risk) vs endoscopic evaluation, which has a risk of complications31
ASGE recommends endoscopic surveillance exclusively in patients with risk factors, but not in the general cohort of patients in whom gastric intestinal metaplasia is detected32
  • AGA = American Gastroenterological Association; ASGE = American Society for Gastrointestinal Endoscopy