Infectious causes of aortitis
Diagnosis | Age at onset | Tissue pattern | Core symptoms and signs | Typical imaging features |
---|---|---|---|---|
Staphylococcus, Streptococcus, Salmonella, or Pseudomonas infection | Any | Suppurative | Fever, constitutional symptoms History of antecedent infection High erythrocyte sedimentation rate and C-reactive protein Positive blood cultures Positive tissue stain and culture | Usually a single lesion |
Syphilis | Decades after primary infection | Lymphoplasmacytic | Possible history of untreated primary syphilis Positive syphilis serology Positive tissue stain and culture | Usually a single lesion in the thoracic aorta |
Coxiella burnetii infection (Q fever) | Usually older, occurs months to years after primary infection | Granulomatous | Possible fever, abdominal pain, high C-reactive protein and erythrocyte sedimentation rate Positive immunoglobulin G Positive polymerase chain reaction of aortic tissue | More often in the abdominal than the thoracic aorta Predilection for existing aneurysms or vascular grafts |
Fungal or mycobacterial infection | Any | Granulomatous (may be suppurative) | Constitutional symptoms Disseminated infection Positive tissue stain and culture | Thoracic or abdominal aorta |
Based on information from references 10–12.