TABLE 1

Infectious causes of aortitis

DiagnosisAge at onsetTissue patternCore symptoms and signsTypical imaging features
Staphylococcus, Streptococcus, Salmonella, or Pseudomonas infectionAnySuppurativeFever, constitutional symptoms
History of antecedent infection
High erythrocyte sedimentation rate and C-reactive protein
Positive blood cultures
Positive tissue stain and culture
Usually a single lesion
SyphilisDecades after primary infectionLymphoplasmacyticPossible history of untreated primary syphilis
Positive syphilis serology
Positive tissue stain and culture
Usually a single lesion in the thoracic aorta
Coxiella burnetii infection (Q fever)Usually older, occurs months to years after primary infectionGranulomatousPossible fever, abdominal pain, high C-reactive protein and erythrocyte sedimentation rate
Positive immunoglobulin G
Positive polymerase chain reaction of aortic tissue
More often in the abdominal than the thoracic aorta
Predilection for existing aneurysms or vascular grafts
Fungal or mycobacterial infectionAnyGranulomatous (may be suppurative)Constitutional symptoms
Disseminated infection
Positive tissue stain and culture
Thoracic or abdominal aorta
  • Based on information from references 1012.