Conditions commonly excluded in psychedelic-assisted therapy trials
| Psychiatric conditions Bipolar disorder (personal or close family history) Personality disorder (eg, antisocial, borderline, schizoid) Psychotic disorder (personal or close family history) Suicidal ideation (with intent or plan) or recent suicidal behavior |
| Nonpsychiatric conditions Arrhythmia (clinically significant) Type 1 diabetes, type 2 diabetes (uncontrolled) Hepatic dysfunction, depending on psychedelic metabolism Uncontrolled hypertension Myocardial infarction (lifetime history) Pregnancy or breastfeeding QTc prolongation Seizure disorder Stroke (lifetime history) Tachycardia Unstable thyroid disease |