TABLE 4

Direct oral anticoagulant use for treatment of venous thromboembolism and nonvalvular atrial fibrillation after bariatric surgery

Gastric bandingAll direct oral anticoagulants can be used because the gastrointestinal anatomy is preserved
Gastric sleeveApixaban may be a preferred option because of the intact duodenum; avoid rivaroxaban and dabigatran because they are predominantly absorbed in the stomach; edoxaban requires an acidic environment for optimal absorption, which may be altered
Roux-en-Y gastric bypass
Biliopancreatic diversion with duodenal switch
All direct oral anticoagulants should be avoided due to inadequate absorption after extensive loss of the stomach and proximal small intestines