Suzetrigine prescribing and cost information
| Indication | Approved by US Food and Drug Administration to treat acute postoperative pain for 14 days |
| Dose | Loading: 100 mg Maintenance: 50 mg every 12 hours |
| Duration | Half-life of 23.6 hours |
| Cost | $15.50 per pill18 (typical course is 2 weeks) |
| Common side effects | Nausea and vomiting, pruritis, rash, muscle spasms, increased serum creatine phosphokinase level |
| Contraindications | Hormonal contraceptives: may impair efficacy Cirrhosis: reduce dose for Child-Pugh class B; do not use in Child-Pugh class C CYP3A substrates: inhibitors may cause accumulation of drug and metabolites; inducers may reduce effect |
Based on information from reference 11.