Paraneoplastic dermatoses associated with internal malignancy
| Dermatoses | Malignancies |
|---|---|
| Acquired ichthyosis Diffuse rhomboid scales on trunk and extensor regions | Hodgkin disease, lymphoproliferative disorders |
| Acrokeratosis paraneoplastica Erythematous desquamating eruption with plaques in acral areas | Squamous cell carcinoma of the upper aerodigestive tract |
| Leser-Trélat syndrome Sudden appearance of multiple seborrheic keratoses | Gastrointestinal adenocarcinoma; multiple carcinomas and lymphomas |
| Necrolytic migratory erythema Migratory erythematous papules or macules in a ringlike pattern | Glucagonoma |
| Acanthosis palmarisa Velvety palms with exaggerated skin ridges | Lung and gastric carcinoma |
↵a Also known as “tripe” palms, as the palms were thought to resemble tripe, a dish made from the rugose foregut of cattle.
Based on information from references 5 and 6.