The Screening Tool of Older Persons’ Potentially Inappropriate Prescriptions (STOPP): Selected warnings and recommendations
| Tricyclic antidepressants | Avoid use with dementia, narrow-angle glaucoma, cardiac conduction abnormality, prostatism, or history of urinary retention because of risk of worsening these conditions |
| Benzodiazepines | No indication for treatment beyond 4 weeks Risk of prolonged sedation, confusion, impaired balance, falls, traffic accidents Withdraw gradually if taken for > 2 weeks because of risk of withdrawal syndrome |
| Proton pump inhibitors | For uncomplicated peptic ulcer disease or erosive peptic esophagitis, discontinue full therapeutic dosage before 8 weeks, or reduce dosage |
| Hypnotic “z” drugs (eg, zopiclone, zolpidem, zaleplon) | May cause protracted daytime sedation, ataxia |
| Antimuscarinic drugs | For overactive bladder with concurrent dementia or chronic cognitive impairment, there is risk of increased confusion, agitation For narrow-angle glaucoma, there is risk of acute exacerbation of glaucoma For chronic prostatism, there is risk of urinary retention |
Based on information in references 60 and 61.