Features of small fiber neuropathy
| Neuropathic pain: burning, numbness, tingling, itching, “frostbite-like” sensations |
| Commonly “stocking-glove” pattern, but may be random, migratory, and intermittent |
| Symptoms of dysautonomia (eg, skin changes, sweating abnormalities, dry eyes, dry mouth, gastrointestinal dysmotility, orthostasis, palpitations, bowel or bladder changes, sexual dysfunction) |
| Normal neurologic examination, nerve conduction studies, needle electromyography |