TABLE 1

Studies discussed in this article

AURA
Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (BY217/M2-124)5
EOS
Effect of Roflumilast on Lung Function in Chronic Obstructive Pulmonary Disease Patients Treated With Salmeterol (BY217/M2-127)4
HELIOS
Effect of Roflumilast in Chronic Obstructive Pulmonary Disease) Patients Treated With Tiotropium (BY217/M2-128)4
HERMES
Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (BY217/M2-125)5
RATIO
Effect of 1-Year Treatment With Roflumilast in Severe Chronic Obstructive Pulmonary Disease3
REACT
Effect Of Roflumilast On Exacerbations In Patients With Severe Chronic Obstructive Pulmonary Disease Uncontrolled By Combination Therapy: A Multicentre Randomised Controlled Trial6
RECORD
Roflumilast—An Oral Anti-inflammatory Treatment for Chronic Obtructive Pulmonary Disease: A Randomised Controlled Trial1