TABLE 1

Conditions associated with thrombotic microangiopathy

Thrombotic thrombocytopenic purpura
Shiga toxin hemolytic uremic syndrome
Atypical hemolytic uremic syndrome (due to activation of the alternate complement pathway)
Antiphospholipid antibody syndrome, often associated with systemic lupus erythematosus
Progressive systemic sclerosis
Infections, eg, human immunodeficiency virus
Pregnancy, preeclampsia, eg, hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome
Drug-induced, eg, mitomycin, gemcitabine, vascular endothelial growth factor inhibitors, quinine, calcineurin inhibitors
Stem cell transplant