TABLE 1

Toolbox essentials

Type of sourcesExamplesCommentsFunding source
Primary sourcesPubMedArticle searches are needed to find answers to questions
May be difficult to use at the point of care in a busy practice
Workflow reminders to look up this information at the end of each day promote lifelong learning
Federal government
Pharmaco-therapyLexicomp, ePocratesPractical information about medications such as indications, dosage, adverse reactions, and drug interactionsAdvertising, subscription, data sharing
Medical calculatorsMDCalcTools to calculate cardiovascular risk, medication dosage adjustment in renal insufficiency, sodium replacement in hyponatremia, moreUnclear
Guidelines databasesNational Guideline Clearing House, USPSTFA searchable collection of guidelines developed by various government-funded or professional societies which allow side-by-side comparisons and ratings for strength of evidence for individual recommendationsFederal government
Systematic reviews of medical evidenceCochrane Collaboration, Centre for Reviews and DisseminationProvide high-quality up-to-date syntheses of research evidence
Robust and unbiased information to help clinicians make decisions
Subscription, university
Evidence search toolsPubMedClinical queries provide busy clinicians fast access to reliable clinical studies using preset research methodology filters
Designed to find those few “good” articles that can help us make decisions at the point of care
Federal government
Online textbooksAccess Medicine, Harrison’s Principles of Internal MedicineEasily accessible and updated more frequently than their print versions
Additional features such as multimedia materials, search capabilities, and ability to share notes turn these into excellent resources, especially for questions that often come up when working with residents or students
Subscription
Online texts and summary sourcesDynamed, UpToDate, Clinical EvidenceFast clinical answers at the point of care
Can be accessed from desktop or mobile devices
Subscription
Internet searchWikipedia, GoogleAn Internet search not directly in a medical reference can provide more information including that from patients and industry, but reliability and validity can limit use without discrimination of results
Google searches can replicate findings from summary sources in speed and accuracy9
Donations (Wikipedia), advertising (Google)