Recommended salvage regimens for Helicobacter pylori
| (After 2 or more failures with different drugs) |
| Furazolidone quadruple therapy with tetracycline Both of the following 4 times a day with meals and at bedtime: Bismuth subsalicylate or bismuth subcitrate 2 tablets Tetracycline hydrochloride 500 mg Plus: Furazolidone 100 mg 3 times a day with meals A proton pump inhibitor twice daily a All for 14 days |
| Furazolidone quadruple therapy with amoxicillin All of the following for 14 days: Bismuth subsalicylate or bismuth subcitrate 2 tablets 4 times daily with meals and at bedtime Furazolidone 100 mg 3 times a day with meals Amoxicillin 1 g 3 times a day with meals A proton pump inhibitor twice daily a |
| Rifabutin therapies (see Table 3) |
These therapies are expected to achieve > 90% (often > 95%) cure rates with susceptible infections and adherent patients.
↵a Preferred proton pump inhibitors are omeprazole 40 mg, lansoprazole 45 or 60 mg, rabeprazole 20 mg, or esomeprazole 20 mg; pantoprazole is not recommended as 40 mg is approximately equivalent to 9 mg omeprazole.