TABLE 1

Differentiating ‘postpartum blues’ from major depressive disorder

Postpartum bluesMajor depressive disorder
Can occur in up to 75% of womenOccurs in up to 20% of women
Resolves by day 10 postpartumPeaks at 3 months postpartum but can extend to up to 12 months
Typical symptoms include mood lability, tearfulness, irritability, confusion, and fatigueSymptoms include low mood or loss of interest or pleasure in normally pleasurable activities for at least 2 weeks in addition to other diagnostic criteria for major depressive disorder
Responds well to support, reassurance, and adequate sleepTreatment often involves both pharmacologic and nonpharmacologic therapy