TABLE 12

Tularemia

Pathogen: Francisella tularensis
Tick vectors: Amblyomma americanum, Dermacentor variabilis, Dermacentor andersoni
Geographic distribution: South-central region
Classic presentation:
Ulceroglandular: Red painful papule at the site of tick exposure that evolves into a black eschar; fever, headache, myalgia, malaise, lymphadenopathy
Glandular: Same as ulceroglandular except primary lesion not recognized
Diagnosis: 4-fold increase between the acute and convalescent sera or a single titer ≥ 1:160; culture may also be performed
Treatment: Streptomycin or gentamicin for at least 10 days; for less severe disease, ciprofloxacin or doxycycline for 14 days