Borrelia miyamotoi infection
| Tick vectors: Ixodes scapularis, Ixodes pacificus |
| Geographic distribution: Northeastern, north- central, and far western regions |
| Classic presentation: Fever, headache, myalgia, arthralgia, gastrointestinal symptoms, meningoencephalitis, thrombocytopenia, elevated aminotransferase levels |
| Diagnosis: No validated test available, though culture, polymerase chain reaction, and serology are performed in research settings |
| Treatment: Doxycycline for 2–4 weeks (based on expert opinion) |