Summary of breast cancer screening guidelines
| Modality | Hereditary breast and ovarian cancer syndrome and hereditary diffuse gastric cancera | Cowden syndrome (PTEN hamartoma tumor syndrome) | Li-Fraumeni syndrome | Peutz-Jeghers syndrome | ||||
|---|---|---|---|---|---|---|---|---|
| Onset (years) | Timing | Onset (years) | Timing | Onset (years) | Timing | Onset (years) | Timing | |
| Breast self-awareness and examination | 18 | Monthly | 18 | Monthly | 18 | Monthly | 18 | Monthly |
| Clinical breast examination | 25 | Every 6-12 months | 25b | Every 6-12 months | 20-25b | Every 6-12 months | 25 | Semiannually |
| Mammography | 30c | Annually | 30-35b | Annually | 30c | Annually | 30 | Annually |
| Breast MRI | 25c | Annually | 30-35b | Annually | 20-29 | Annually | 25 | Annually |
↵a The National Comprehensive Cancer Network recommends following hereditary breast and ovarian cancer syndrome management for breast cancer risk in hereditary diffuse gastric cancer
↵b Or 5-10 years before the earliest known breast cancer in the family, whichever is earlier
↵c Individualized on the basis of family history
Information from references 6, 26, and 28.