Pharmacokinetic profile of insulin preparations in healthy people
| Insulin | Onset of action | Peak effect | Duration | Frequency of administration |
|---|---|---|---|---|
| Glargine | 2 hours | No peak | 24 hours | Once daily |
| Detemir | 2 hours | 3–9 hours | 12–24 hours | Once or twice daily |
| Neutral protamine | 1–2 hours | 4–8 hours | 12–18 hours | Once or twice daily |
| Hagedorn | ||||
| Lispro, glulisine, aspart | 5–15 minutes | 1–2 hours | 4–6 hours | Before or after each meal |
| Regular | 30 minutes | 2–4 hours | 6–8 hours | With meals or every 6 hours for patients on continuous tube feeding |