TABLE 4

Prognostic scores of acute liver failure

FactorKing’s College criteria37,66,67Clichy criteria66,69MELD score68APACHE score
AgeYesYesNoYes
Cause of acute liver failureYesNoNoNo
Presence of encephalopathyYesYesNoNo
Presence of coagulopathyYesYesYesNo
Serum bilirubin levelYesNoYesNo
Serum creatinine levelYesNoYesYes
Sensitivity to predict poor outcome without liver transplant
 Acetaminophen-induced acute liver failure69%75%60%68%
 Acute liver failure from other causes68%69%87%
Specificity to predict poor outcome without liver transplant
 Acetaminophen-induced acute liver failure82%56%69%87%
 Acute liver failure from other causes92%50%65%
  • APACHE II = Acute Physiology and Chronic Health Evaluation II; MELD = Model for End-State Liver Disease