Percutaneous mitral valve repair devices
| Type of repair | Device | Technique | Status |
|---|---|---|---|
| Edge-to-edge repair | MitraClip | V-shaped clip applied via femoral vein | FDA approval for patients with degenerative mitral regurgitation COAPT trial for patients with functional mitral regurgitation CE Mark approval for all mitral regurgitation |
| Indirect annuloplasty | Carillon | Nitinol wire placed in the coronary sinus via the internal jugular vein | US trial being planned CE Mark approval |
| Direct annuloplasty | Mitralign | Anchors placed in the posterior annulus via femoral artery | Feasbility trial published |
| Valtech Cardioband | Anchors placed in the posterior annulus via the femoral vein | Feasibility trial published | |
| Chordal repair | NeoChord | Transapical approach | CE Mark approval |
| Valve spacer | Mitra-Spacer | Balloon placed in the mitral valve to reduce regurgitant orifice and improve coaptation, transfemoral and transapical delivery | First-in-man completed9 Technology licensed for possible tricuspid valve use |
| Chamber remodeling | Basal annuloplasty of the cardia externally (BACE) | Silicone band placed externally at the atrioventricular groove and inflated | First-in-man completed10 |
FDA = US Food and Drug Administration