Olin et al8 (2012)
First publication from the US Registry Extracranial carotid FMD is as common as renal FMD Defined common symptoms, including hypertension, headache, and pulsatile tinnitus
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Kim et al10 (2013)
Only 8.5% of registrants were male Renal involvement was higher in men than in women (89.7% vs 74.1%); extracranial involvement was more common in women than in men (74.9% vs 44.1%) Compared with women, men were twice as likely to have an aneurysm (40.8% vs. 20.4%) or dissection (39.6% vs 20.0%) Renal artery dissection with flank pain and infarction was a pattern of disease presentation in men with FMD
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Weinberg et al11 (2015)
High rate of antiplatelet and antihypertensive therapy among registrants 72.9% of FMD patients were on antiplatelet therapy (58.8% on aspirin alone, 4.6% on clopidogrel only) 71.7% of patients were on antihypertensive medications, with 21.5% on three or more
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Green et al12 (2016)
Mean age at the time of diagnosis in pediatric patients was 8.4 ± 4.8 years Significantly more male patients in the pediatric FMD population vs the adult FMD population (42.2% vs 6.0%) Compared with adults, pediatric patients more likely to have renal artery involvement (97% vs 69.7%) and mesenteric artery involvement (38.9% vs 16.2%) More pediatric FMD patients than adult FMD patients reported having a family member with FMD (17.2% vs 4.7%)
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Kadian-Dodov et al7 (2016)
21.7% of patients in the registry had an aneurysm, 25.7% had a dissection, and 41.7% had an aneurysm or dissection Roughly one-third of patients with aneurysm required intervention, most commonly for those found in the extracranial carotid, renal, and intracranial arteries
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O’Connor et al3 (2016)
34.5% of patients in the registry were current or former smokers Smoking history was associated with worse outcomes than in nonsmokers, including an increased need for revascularization (45.9% vs 36.7%), and a higher likelihood of aneurysm (24.8% vs 18.9%) and adverse symptoms such as claudication (15.1% vs 7.4%)
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