Angiotensin-neprilysin inhibition for managing heart failure
| Generic name | Dosing range |
|---|---|
| Sacubitril-valsartan | 24–26 mg, 49–51 mg, or 97–103 mg twice daily If tolerated for 2–4 weeks, double the daily dose until target dose of 97–103 mg twice daily is reached For patients converting from an ACE inhibitor, this medication should be started 36 hours after discontinuation of the ACE inhibitor |