TABLE 3

MED-PED diagnostic criteria for probable heterozygous familial hypercholesterolemia

Age	Closest relative with familial hypercholesterolemia
	First-degree		Second-degree		Third-degree		None

	Threshold cholesterol level (mg/dL) in the patient
	Total	LDL-C	Total	LDL-C	Total	LDL-C	Total	LDL-C
< 20	220	155	230	165	240	170	270	200
20–29	240	170	250	180	260	185	290	220
30–39	270	190	280	200	290	210	340	240
≥ 40	290	205	300	215	310	225	360	260

Reprinted from Williams RR, Hunt SC, Schumacher MC, et al. Diagnosing heterozygous familial hypercholesterolemia using new practical criteria validated by molecular genetics. Am J Cardiol 72(2):171–176, copyright 1993, with permission from Elsevier.