Contraindications and precautions to the use of influenza vaccines

History of a severe allergic reaction such as anaphylaxis to a previous dose of any influenza vaccine, regardless of the component suspected(including eggs)Moderate or severe acute illness with or withoutfever
History of Guillain-Barré syndrome within 6 weeksafter influenza vaccination
For the live-attenuated quadrivalent influenza vaccine only:
Concomitant aspirin-or salicylate-containing therapy in children and adolescents
Children 2 to 4 years old who have diagnosed asthma or whose parents or caregivers report that a healthcare provider has told them during the past 12 months that their child had wheezing or asthma, or whose medical record indicates a wheezing episode in the past 12 months
Children and adults who are immunocompromised due to any cause including immunosuppressive medications and human immunodeficiency virus infection
Close contacts and caregivers of severely immunosuppressed persons who require care in a protected environment
Receipt of influenza antiviral medication within the past 48 hours
Asthma in persons age 5 and older
Other underlying medical conditions that may predispose to complications after wild-type influenza infection:
 Chronic pulmonary disease
 Cardiovascular disease, excluding isolated hypertension
 Renal, hepatic, neurologic, hematologic, or metabolic disorders including diabetes mellitus
  • Adapted from reference 4.