Natural history of peripheral artery disease
| Symptoms at diagnosis in patients with PAD | Patients (%) | 5-Year outcomes |
|---|---|---|
| Asymptomatic | 20–50 | Major adverse limb events |
| Atypical leg discomfort | 40–50 | Stable claudication: 70%–80% |
| Claudication | 10–30 | Lower extremity revascularization: 10%–20% |
| Critical limb ischemia: 1%–2% | ||
| Major adverse cardiovascular events | ||
| Myocardial infarction/stroke: 20% | ||
| Death: 15%–30% | ||
| 1-year outcomes | ||
| Critical limb ischemia | 1–2 | Amputation: 25% |
Source: Data from reference 6.