Advantages of selected type 2 diabetes drugs
| Drug | Cardiovascular benefit | Weight loss | Low risk of hypoglycemia | Low cost |
|---|---|---|---|---|
| Metformin | Yes | Yes | Yes | |
| Sulfonylureas | Yes | |||
| Meglitinides | ||||
| GLP-1 agonists | Yes | Yes | Yes | |
| DPP-4 inhibitors | Yes | Yes | ||
| SGLT2 inhibitors | Yes | Yes | Yes | |
| Thiazolidinediones | Yes | |||
| Colesevelam | Yes | |||
| Alpha-glucosidase inhibitors | Yes | |||
| Pramlintide | Yes | |||
| Bromocriptine | Yes | |||
| Insulin | Varies by formulation |
DPP-4 = dipeptidyl peptidase 4; GLP-1 = glucagon-like peptide 1; SGLT2 = sodium-glucose cotransporter 2