JNC 7 and JNC 8 guidelines compared
| JNC 72 | JNC 84 | |
|---|---|---|
| Methodology | Nonsystematic literature review by expert committees | Systematic review of randomized controlled trials |
| Treatment goal (mm Hg) | < 140/90 for most patients < 130/80 for patients with diabetes < 130/80 for patients with chronic kidney disease | < 140/90 for < 60 years old < 150/90 for ≥ 60 years old |
| Drug therapy | Recommended use of 5 drug classes; thiazide diuretic for initial treatment in most cases | Recommended 4 classes of drugs to be used; thiazide diuretic, angiotensin-converting enzyme inhibitor, angiotensin II receptor blocker, or calcium channel blocker |
| Special recommendations | Heart failure, postmyocardial infarction, high coronary disease risk, diabetes, chronic kidney disease, and recurrent stroke prevention | Black and nonblack patient groups, chronic kidney disease, and diabetes |
| Lifestyle recommendations | Based on literature review and expert opinion | Endorsed the evidence-based findings of the Lifestyle Work Group |
JNC = Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure