TABLE 6

MGUS: When to refer patients to a hematologist

Intermediate- and high-risk MGUS
Suspicion of multiple myeloma or other concomitant malignancy
Suspicion of light chain amyloidosis (including abnormal serum free light chain ratio), for help with diagnostic workup
Possible MGUS-related disorders (peripheral neuropathy, monoclonal gammopathy of renal significance)
  • MGUS = monoclonal gammopathy of undetermined significance