Factors favoring levothyroxine therapy in subclinical hypothyroidism
| Thyroid-stimulating hormone (TSH) level > 2 times the upper limit of normal or > 8 mIU/L Progressive rise in TSH Goiter Positive antithyroid antibodies Pregnancy or planning pregnancy Infertility or ovulatory dysfunction Childhood or adolescence Dyslipidemia Established cardiovascular disease or risk factors for cardiovascular disease Depression or bipolar disease Therapeutic trial for clinical symptoms of hypothyroidism Patient preference |