Infectious Diseases

  • Viruses change; we can, too
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine March 2023, 90 (3) 135-136; DOI: https://doi.org/10.3949/ccjm.90b.03023

    As we learn more about the mpox (formerly monkeypox) virus, Sossai et al in this issue of the Journal discuss how our understanding of its link to variola has led to therapeutic and prophylactic vaccination options.

  • Smallpox and monkeypox: Looking back and looking ahead
    Paolo Sossai, MD, PhD, Domenico Staiti, MD, Massimiliano Cannas, MD and Piero Grima, MD
    Cleveland Clinic Journal of Medicine March 2023, 90 (3) 141-144; DOI: https://doi.org/10.3949/ccjm.90a.22067

    Two vaccines have been developed for mpox prevention, but clarity is needed on when and how to use them.

  • Central vision loss in a 44-year-old woman
    Walker M. Schmidt, BS, Nirosha D. Perera, MD, Blake H. Fortes, MD, Benjamin A. Nelson, MD, Wendy M. Smith, MD and Hannah C. Nordhues, MD
    Cleveland Clinic Journal of Medicine January 2023, 90 (1) 35-41; DOI: https://doi.org/10.3949/ccjm.90a.22038

    The patient had a wide range of symptoms and comorbidities, resulting in a complicated differential diagnosis. Careful evaluation eventually led to a focus on sexually transmitted infection.

  • Test ordering: Balancing the good for the many with the good for the one
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine December 2022, 89 (12) 672-673; DOI: https://doi.org/10.3949/ccjm.89b.12022

    Three articles this month address how we order clinical tests, one on the question of treating the patient with asymptomatic bacteriuria, the others on the advantages and disadvantages of standing orders for “daily labs” for inpatients.

  • Does my patient need to be screened or treated for a urinary tract infection?
    Ellen K. Kendall and Yael Mauer, MD, MPH
    Cleveland Clinic Journal of Medicine December 2022, 89 (12) 695-698; DOI: https://doi.org/10.3949/ccjm.89a.21121

    When patients present with symptoms that suggest but are not clearly diagnostic of urinary tract infection, urine studies should be obtained.

  • Another vaccine article? Yes, but a different vaccine
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine November 2022, 89 (11) 607-608; DOI: https://doi.org/10.3949/ccjm.89b.11022

    As newer vaccines against Streptococcus pneumoniae have arrived, so have confusing recommendations and guidelines for the sequence and timing of administration.

  • Update on pneumococcal vaccination in adults: Simpler is better
    Craig D. Nielsen, MD, FACP, Joel A. Kammeyer, MD, MPH, FACP and Michael J. Tan, MD, FACP, FIDSA
    Cleveland Clinic Journal of Medicine November 2022, 89 (11) 640-642; DOI: https://doi.org/10.3949/ccjm.89a.22047

    Recommendations have been updated in the hopes not only of preventing more cases of invasive pneumococcal disease, but also of making the recommendations easier to follow.

  • Mucormycosis presenting as dental pain
    Pankaj Garg, MS, MBBS, Aalam Sohal, MD and Sankalp Mittal, MDS
    Cleveland Clinic Journal of Medicine October 2022, 89 (10) 553-555; DOI: https://doi.org/10.3949/ccjm.89a.22001

    A root canal procedure failed to relieve the pain, and 1 week later the patient developed mobility of the left upper teeth.

  • Diagnostic stewardship for urinary tract infection: A snapshot of the expert guidance
    Glenn T. Werneburg, MD, PhD and Daniel D. Rhoads, MD
    Cleveland Clinic Journal of Medicine October 2022, 89 (10) 581-587; DOI: https://doi.org/10.3949/ccjm.89a.22008

    New guidance on ordering, processing, and reporting urine cultures focuses on reducing unnecessary antibiotic use and the misdiagnosis of urinary tract infection.

  • Confusion in a 22-year-old woman, and diagnostic uncertainty
    Brian Elliott, MD, Christopher Newey, DO, MS, Katelynn Alcorn, MPH and Luke McCoy, MD
    Cleveland Clinic Journal of Medicine October 2022, 89 (10) 589-595; DOI: https://doi.org/10.3949/ccjm.89a.20176

    The patient had been complaining of gradual-onset and progressive headache and neck and back pain for 3 weeks.

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