Infectious Diseases

  • Treating anemia: It’s not just the EPO
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 174-175; DOI: https://doi.org/10.3949/ccjm.89b.04022

    Long-term effects of treatment with the new oral inhibitors of prolyl hydroxylase will need to be carefully monitored, as prolyl hydroxylase is a key structural component of diverse proteins.

  • Glycemic targets in the ICU: A look back, and ahead
    Keren Zhou, MD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 189-190; DOI: https://doi.org/10.3949/ccjm.89a.21127

    Much work is still needed to understand the nuances of glycemic targets in critically ill patients, and to learn how to take advantage of evolving technology to improve glycemic control.

  • Glycemic control in the critically ill: Less is more
    Ghaith Alhatemi, MD, Haider Aldiwani, MD, Rafal Alhatemi, MD, Marwah Hussein, MD, Suzan Mahdai, MD and Berhane Seyoum, MD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 191-199; DOI: https://doi.org/10.3949/ccjm.89a.20171

    The authors discuss findings from key trials, metrics of glycemic control, and recommendations of professional societies for target blood glucose ranges in critically ill patients.

  • Potential systemic benefits of shocking or blocking nerves
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 119-120; DOI: https://doi.org/10.3949/ccjm.89b.03022

    What has really caught my attention is the expanding research on controlled regional neuromodulation and its impact on systemic physiology and inflammation.

  • Unilateral pulmonary edema
    Yoshihiro Harano, MD and Mikio Nakajima, MD, MPH, PhD
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 124-125; DOI: https://doi.org/10.3949/ccjm.89a.21046

    Three weeks after discharge from hospitalization for COVID-19, the patient noted progressively worsening exertional dyspnea and fatigue.

  • Stellate ganglion block as a treatment for vasomotor symptoms: Clinical application
    Stellate ganglion block as a treatment for vasomotor symptoms: Clinical application
    Yeonsoo Sara Lee, BS, Christopher Wie, MD, Scott Pew, MD and Juliana M. Kling, MD, MPH
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 147-153; DOI: https://doi.org/10.3949/ccjm.89a.21032

    Hormone therapy is the mainstay of treatment, but there is a clear need for safe and effective nonhormonal options. The authors review data on the use of stellate ganglion block in perimenopausal and postmenopausal patients.

  • Common skin signs of COVID-19 in adults: An update
    Samantha Polly, MD and Anthony P. Fernandez, MD, PhD
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 161-167; DOI: https://doi.org/10.3949/ccjm.89a.21126

    Cutaneous findings can be clues to the diagnosis and infection severity in viral illnesses, including COVID-19.

  • Sometimes the look is worth the walk
    Brian F. Mandell, MD
    Cleveland Clinic Journal of Medicine January 2022, 89 (1) 4-5; DOI: https://doi.org/10.3949/ccjm.89b.01022

    We do not routinely look at blood smears today. The need for expediency and efficiency limit the time spent on activities with a low yield for influencing care. And yet, for some conditions in some patients, going back to the basics can be clinically rewarding, and even memorable.

  • Cardiac considerations in liver transplantation
    Cardiac considerations in liver transplantation
    Vikram Sharma, MD, MD(Res), Cerise Kleb, MD, Chirag Sheth, MD, Beni Rai Verma, MD, Vardhmaan Jain, MD, Ruchi Sharma, MD, MS, Parth Parikh, MD, Jacek Cywinski, MD, K. V. Narayanan Menon, MD, FAASLD, Jamak Modaresi Esfeh, MD, Bijan Eghtesad, MD, Cristiano Quintini, MD, Teresa Diago Uso, MD, Michael Z. Y. Tong, MD, Ravi Nair, MD, Ajay Bhargava, MD and Maan Fares, MD
    Cleveland Clinic Journal of Medicine January 2022, 89 (1) 46-55; DOI: https://doi.org/10.3949/ccjm.89a.21006

    Today’s transplant patients are older and more likely to have cardiac comorbidities, and effects of advanced liver disease on the circulatory system pose challenges in perioperative management.

  • Megaloblastic anemia due to severe vitamin B12 deficiency
    Nellowe Candelario, MD and Catherine Klein, MD
    Cleveland Clinic Journal of Medicine January 2022, 89 (1) 8-9; DOI: https://doi.org/10.3949/ccjm.89a.21041

    The 75-year-old patient presenting with altered mental status and pancytopenia had a history of peptic ulcer disease and subtotal gastrectomy.

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