Epilepsy
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Pathogenesis of epilepsy: the role of excitatory amino acids
Gregory L. Holmes, MD- Cleveland Clinic Journal of Medicine July 1995, 62 (4) 240-247;
These neurotransmitters seem to play a role in brain development—and also in seizures. Experimental drugs can block their action.
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Recurrence, remission, and relapse of seizures
Norman K. So, MB, BChir- Cleveland Clinic Journal of Medicine November 1993, 60 (6) 439-444;
Drug treatment after a first seizure reduces the risk of recurrence by about half, but many patients find the adverse effects intolerable.
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Experimental limbic epilepsy: models, pathophysiologic concepts, and clinical relevance
Mohamed Nayel, MD, Issam A. Awad, MD, Mark Larkins, MD and Hans Lüders, MD, PhD- Cleveland Clinic Journal of Medicine November 1991, 58 (6) 521-530;
Complex partial seizures originating in the temporal lobe are common in epilepsy patients. Drug treatment is often ineffective. What predisposes a patient to these seizures? How do they occur? Animal studies are providing clues to the puzzle.
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Surgery for intractable epilepsy
Melinda L. Estes, MD, Harold H. Morris III, MD, Hans Lüders, MD, Alden W. Dudley Jr., MD, Ronald P. Lesser, MD, Dudley S. Dinner, MD, Diane Friedman, RN, CS, Joseph F. Hahn, MD and Elaine Wyllie, MD- Cleveland Clinic Journal of Medicine September 1988, 55 (5) 441-447;
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Intractable seizure disorders of childhood
A. David Rothner, M.D- Cleveland Clinic Journal of Medicine September 1984, 51 (3) 505-510;
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Corpus callosum section for seizure control: rationale and review of experimental and clinical data
Warren T. Blume, M.D- Cleveland Clinic Journal of Medicine June 1984, 51 (2) 319-332;
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Evaluation of the child with seizures
A. David Rothner, M.D- Cleveland Clinic Journal of Medicine June 1984, 51 (2) 267-272;
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Antiepileptic Drug Development Program
Roger J. Porter, M.D, James J. Cereghino, M.D, Gill D. Gladding, R.Ph, Bettiejean Hessie, B.S, Harvey J. Kupferberg, Ph.D, Barrett Scoville, M.D and Billy G. White, Ph.D- Cleveland Clinic Journal of Medicine June 1984, 51 (2) 293-305;
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Surgical techniques for relief from seizures
Joseph F. Hahn, M.D and Margot Sellers- Cleveland Clinic Journal of Medicine June 1984, 51 (2) 307-311;
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Generalized epilepsies: a review
Hans Lüders, M.D., Ph.D, Ronald P. Lesser, M.D, Dudley S. Dinner, M.D and Harold H. Morris III, M.D- Cleveland Clinic Journal of Medicine June 1984, 51 (2) 205-226;